Epigenetics
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Epigenetics
Epigenetics is a subfield of genetics that studies the relationships of phenotypic expressions defined by histone modifications, DNA methylations on CpG islands and chromatin conformations.
Bisulfite conversion is used to sequence the methylation patterns of genomic DNA to determine whether cytosine is methylated or not. In collaboration with Celemics, we offer Methyl-seq target enrichment panels that allow you to monitor cytosine methylation in selected genes.
Celemics' patented dual probe design incorporating bisulfite conversion enables precise analysis of the methylation status of target genes. Celemics' methylation sequencing panel provides unparalleled performance for methylation status analysis for plasma DNA.
- Targeted methylation sequencing is processed using the bisulfite conversion process in the NGS workflow.
- The hybridization probe and methylation adapters are designed with bisulfite conversion sequence alteration in mind.
- Only selective genes can be targeted for analysis, which allows for reduced sequencing costs.
Technical details about Epigenetics
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- Producer: Celemics, Inc.
Epigenetics
Epigenetics is a subfield of genetics that studies the relationships of phenotypic expressions defined by histone modifications, DNA methylations on CpG islands and chromatin conformations.
Bisulfite conversion is used to sequence the methylation patterns of genomic DNA to determine whether cytosine is methylated or not. In collaboration with Celemics, we offer Methyl-seq target enrichment panels that allow you to monitor cytosine methylation in selected genes.
Celemics' patented dual probe design incorporating bisulfite conversion enables precise analysis of the methylation status of target genes. Celemics' methylation sequencing panel provides unparalleled performance for methylation status analysis for plasma DNA.
- Targeted methylation sequencing is processed using the bisulfite conversion process in the NGS workflow.
- The hybridization probe and methylation adapters are designed with bisulfite conversion sequence alteration in mind.
- Only selective genes can be targeted for analysis, which allows for reduced sequencing costs.
- Producer: Celemics, Inc.