Panels using molecular inversion probes

What if you had the panel ready before lunch?

• Extremely fast extremely easy TERGETED PANELS

• Pre-defined panels and custom panels up to 300 genes

• Compatible with Illumina and AVITI sequencers

• Innovative InniSeq protocol allows users to pool samples after the first step. It saves time and consumed plastic and minimizes the occurrence of human error.

• Total preparation time: 190 minutes

  1. Panel annealing: 2:10 hrs

  2. Target extension: 10 min

  3. Exonuclease: 15 min

  4. Barcoding: 35 min

  5. Clean up: 20 min

1. Oncology Panels

Tissue Specific Panel

Bladder Cancer Panel, Expanded BRCA Panel, Colorectal and Pancreatic Cancer Panel, Gastric and Esophageal Cancer Panel, Gynecological Cancer Panel, HRR Pathway Panel, Kidney Cancer Panel, Liver Cancel Panel, Lymphoma Cancer Panel, Melanoma Panel, Prostate Panel

Comprehensive Tumor Panel

Gene list: AKT3, ALK, APC, AR, ARID1A*, ATM, ATR, BAP1, BARD1, BCL2, BCL6, BRAF, BRCA1, BRCA2, BRIP1, BTK, CARD11, CCND1, CCND2, CCND3*, CCNE1*, CD79A*, CD79B, CDH1, CDK12, CDK4, CDK6, CDKN2A, CEBPA*, CHEK1, CHEK2*, CREBBP*, CSF1R, CTNNB1, DDR2, DNMT3A*, EGFR, EP300, ERBB2, ERBB3, ERBB4, ERCC1, ERCC2, ERG, ESR1, EZH2, FAM175A, FANCI, FANCL, FBXW7, FGF1, FGF10, FGF14, FGF19, FGF2, FGF23, FGF3, FGF4*, FGF5, FGF6, FGF7, FGF8*, FGF9, FGFR1, FGFR2, FGFR3*, FGFR4, FLT1, FLT3, FOXL2, GEN1, GNA11, GNAQ, GNAS*, HNF1A, HRAS, IDH1, IDH2, INPP4B, JAK2, JAK3, KDR, KIT, KRAS*, LAMP1, MAP2K1, MAP2K2, MCL1, MDM2, MDM4, MET, MLH1, MLL*, MLLT3, MPL, MRE11A, MSH2, MSH3, MSH6, MTOR, MUTYH, MYC, MYCL1, MYCN*, MYD88, NBN, NF1, NOTCH1*, NOTCH2, NOTCH3*, NPM1, NRAS, NRG1, PALB2, PDGFRA, PDGFRB, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3R1, PMS2, PPP2R2A, PTCH1, PTEN, PTPN11, RAD51, RAD51B, RAD51C, RAD51D, RAD54L, RAF1, RB1, RET, RICTOR, ROS1, RPS6KB1, SLX4, SMAD4, SMARCB1, SMO, SRC, STK11, TERT, TET2, TFRC, TP53, TSC1, TSC2, VHL, XRCC2​

Short Oncology Panel

Gene list:NRAS G12, G13, Q61, K117, A146; KRAS G12, G13, Q61,K117, A146; BRAF V600 EGFR Exons: 18, 19, 20, 21; PIK3CA Exons: 1, 9, 20

2. Hematology Panels

Myeloid Malignancies Panel

Gene list: ASXL1*, BCOR, BCORL1, BRAF*, BRCC3, CALR*, CBL*, CEBPA, CSF1R*, CSF3R*, DDX41*, DNMT3A, ETV6*, EZH2, FLT3 TKD*, FLT3_ITD*, GATA2*, GNAS*, GNB1*, IDH1*, IDH2*, JAK2*, KDM6A, KIT*, KRAS*, MPL*, NF1, NPM1*, NRAS*, PDS5B, PHF6, PPM1D*, PTPN11*, RAD21, RUNX1, SETBP1*, SF3B1*, SMC1A*, SMC3, SRSF2*, STAG2, TET2, TP53, U2AF1*, WT1, ZNF687*, ZRSR2​

Diffuse Large B-Cell Lymphoma Panel

Gene list:ACTB, ACTG1, ANKRD11, ARID1A, ARID1B, B2M, BCL10, BCL2, BCL6, BCL7A, BCOR, BTG1, BTG2, C4B_2, CARD11, CCND3, CD58, CD70, CD79B, CIITA, CREBBP, DAZAP1, DTX1, DUSP2, EP300, EBF1, ETS1, EZH2, FAS, FOXO1, GNA13, GNAI2, GRHPR, HLA-A, HLA-B, HLA-C, HIST1H1B, HIST1H1C, HIST1H1D, HIST1H2AC, HIST1H2AM, HIST1H1E, ITPKB, IRF2BP2, IRF4, IRF8, KLHL14, KLHL6, KLF2, KMT2D, LTB, MEF2B, MPEG1, MYC, MYD88, NFKBIE, NOTCH2, OSBPL10, P2RY8, PAX5, PIM1, PIM2, PLEC, PRDM1, SETD1B, SGK1, SOCS1, SPEN, STAT3, TBL1XR1, TET2, TMSB4X, TNFAIP3, TNFRSF14, TOX, TP53, TRIOBP, TTN, UBE2A, VMP1, WDFY4, ZC3H12A, ZEB2, ZFP36L1

B-Cell Clonality Panel

3. Custom tailored panels

4. Bioinformatic analysis pipeline